"Tru Niagen hair loss" refers to the potential side effect of hair loss associated with the use of the dietary supplement Tru Niagen, which contains a form of NAD+ (nicotinamide adenine dinucleotide) called nicotinamide riboside (NR). NAD+ is a coenzyme involved in various cellular processes, and NR is a precursor to NAD+.
The exact mechanism by which Tru Niagen may cause hair loss is not fully understood, but it is thought to be related to the increased levels of NAD+ in the body. NAD+ is involved in energy metabolism, DNA repair, and cell signaling, and it is possible that the increased levels of NAD+ caused by Tru Niagen may disrupt these processes and lead to hair loss.